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Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice.
Nat Commun. 2023 Sep 2;14(1):5333. doi: 10.1038/s41467-023-41016-z.
Nat Commun. 2023.
PMID: 37660049
Free PMC article.
Succinate based polymers drive immunometabolism in dendritic cells to generate cancer immunotherapy.
Inamdar S, Suresh AP, Mangal JL, Ng ND, Sundem A, Behbahani HS, Rubino TE Jr, Shi X, Loa ST, Yaron JR, Hitosugi T, Green M, Gu H, Curtis M, Acharya AP.
Inamdar S, et al. Among authors: ng nd.
J Control Release. 2023 Jun;358:541-554. doi: 10.1016/j.jconrel.2023.05.014. Epub 2023 May 15.
J Control Release. 2023.
PMID: 37182805
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Succinate in the tumor microenvironment affects tumor growth and modulates tumor associated macrophages.
Inamdar S, Suresh AP, Mangal JL, Ng ND, Sundem A, Behbahani HS, Rubino TE Jr, Yaron JR, Khodaei T, Green M, Curtis M, Acharya AP.
Inamdar S, et al. Among authors: ng nd.
Biomaterials. 2023 Oct;301:122292. doi: 10.1016/j.biomaterials.2023.122292. Epub 2023 Aug 26.
Biomaterials. 2023.
PMID: 37643489
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Short term, low dose alpha-ketoglutarate based polymeric nanoparticles with methotrexate reverse rheumatoid arthritis symptoms in mice and modulate T helper cell responses.
Mangal JL, Inamdar S, Suresh AP, Jaggarapu MMCS, Esrafili A, Ng ND, Acharya AP.
Mangal JL, et al. Among authors: ng nd.
Biomater Sci. 2022 Nov 22;10(23):6688-6697. doi: 10.1039/d2bm00415a.
Biomater Sci. 2022.
PMID: 36190458
Free PMC article.
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Biomaterial mediated simultaneous delivery of spermine and alpha ketoglutarate modulate metabolism and innate immune cell phenotype in sepsis mouse models.
Inamdar S, Tylek T, Thumsi A, Suresh AP, Jaggarapu MMCS, Halim M, Mantri S, Esrafili A, Ng ND, Schmitzer E, Lintecum K, de Ávila C, Fryer JD, Xu Y, Spiller KL, Acharya AP.
Inamdar S, et al. Among authors: ng nd.
Biomaterials. 2023 Feb;293:121973. doi: 10.1016/j.biomaterials.2022.121973. Epub 2022 Dec 17.
Biomaterials. 2023.
PMID: 36549041
Free PMC article.
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